March 22, 2023

Restylane® and Juvéderm®: Which is Right for Your Clients?

Moxie Team

For medspa owners and cosmetic nurses, understanding key differences and benefits between dermal fillers like Restylane® and Juvéderm® is essential.

In this 101 guide, we'll compare and contrast Restylane® vs. Juvéderm® to help you better understand which product is the right fit for you and your individual clients. 

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Understanding the Differences Between Restylane® and Juvéderm®

As an aesthetic nurse, it's crucial to understand the unique qualities of Restylane® and Juvéderm®. While both of these dermal fillers share a foundation of hyaluronic acid, they differ in their formulation and properties.

Restylane® is composed of biocompatible, non-animal stabilized hyaluronic acid, making it an excellent choice for those looking for natural and safe results. In contrast, Juvéderm® utilizes Vycross™ technology, resulting in a smooth, cohesive gel composition. This technology enhances its durability and flexibility for precise placement.

These differences in consistency and formulation translate into distinct treatment outcomes. 

Restylane® provides more structure and lift, making it suitable for areas requiring significant volume enhancement. On the other hand, Juvéderm® offers a smooth and even distribution under the skin, making it ideal for addressing fine lines and wrinkles.

Comparing the Effectiveness of Restylane® and Juvéderm®

Both Restylane® and Juvéderm® have established their effectiveness in addressing various skin concerns. However, their performance may vary depending on the specific area being treated.

Restylane® has demonstrated remarkable results in improving nasolabial folds, marionette lines, and enhancing lip fullness. These are areas that often require more structural support and volume, and Restylane® excels in delivering these desired outcomes.

Juvéderm®, on the other hand, is frequently chosen for treating fine lines around the mouth, under-eye hollows, and vertical lip lines. Its smooth consistency and ability to spread evenly make it a preferred option for achieving a youthful and refreshed appearance in these areas.

When it comes to nasolabial folds, Restylane® has been found to provide outstanding results. These folds, often referred to as smile lines or laugh lines, are the creases that run from the sides of the nose to the corners of the mouth. They tend to become more pronounced with age, contributing to a tired or aged look. Restylane® effectively fills in these folds, restoring a more youthful and rejuvenated appearance.

In contrast, Juvéderm® has gained popularity for its ability to address under-eye hollows. These hollows can create a tired and sunken appearance, making individuals appear older than they actually are. By administering Juvéderm® to the under-eye area, we can fill in these hollows, resulting in a refreshed and well-rested appearance.

The Manufacturers Behind the Popular Dermal Fillers

As an aesthetic nurse contemplating the choice between Restylane® and Juvéderm®, it's essential to consider the manufacturers behind these renowned products.


Restylane® is proudly developed by Galderma, a pharmaceutical company with over 35 years of expertise in dermatology. Galderma has earned its reputation as a trusted name in the industry due to its commitment to scientific excellence and patient satisfaction.

Galderma's dedication to research and development has led to the creation of innovative products catering to specific needs. For instance, Restylane® Lyft is designed for midface volume restoration, offering a solution for those seeking to regain youthful contours. Restylane® Silk is specially formulated to enhance the lips, providing a subtle and natural-looking augmentation.

What sets Galderma apart is not only its commitment to scientific excellence but also its emphasis on patient satisfaction. The company recognizes that each individual is unique, and their products are designed with this in mind. Restylane® offers a range of options, allowing healthcare professionals to tailor treatments to meet the specific needs and desires of their patients.


Juvéderm® is manufactured by Allergan, a global leader in medical aesthetics. With a rich history spanning several decades, Allergan has consistently pushed the boundaries of innovation in the field. Their advanced technology and commitment to excellence ensure that Juvéderm® delivers natural-looking results with a high level of patient satisfaction.

Allergan's dedication to innovation is evident in the diverse range of products within the Juvéderm® line. Juvéderm® Voluma, for example, is specifically formulated to add volume to the cheeks, providing a non-surgical option for those seeking a more youthful appearance. Additionally, Juvéderm® Volbella offers a solution for enhancing the lips, with a focus on achieving natural and harmonious results.

What sets Allergan apart is not only their cutting-edge technology but also their commitment to safety. Allergan prioritizes the well-being of their patients, ensuring that each product undergoes rigorous testing and meets the highest standards of quality. This dedication to safety and efficacy has earned Allergan the trust and confidence of healthcare professionals and patients alike.

Read more about the benefits and use cases for Juvederm.

Pros and Cons of Restylane® and Juvéderm®

Now, let's explore the pros and cons of both Restylane® and Juvéderm® at a glance. 



  • Provides structure and lift, ideal for volume enhancement.
  • Effective in improving nasolabial folds, marionette lines, and enhancing lip fullness.
  • Offers a range of specialized products for various needs.
  • Developed by Galderma, a trusted name in dermatology.


  • May require more maintenance for certain areas due to its structural nature.



  • Smooth consistency allows for even distribution, perfect for fine lines and wrinkles.
  • Excellent for treating under-eye hollows and vertical lip lines.
  • Offers a range of products, including Juvéderm® Voluma for cheek volume.
  • Manufactured by Allergan, a global leader in medical aesthetics.


  • May require more frequent touch-ups for certain individuals.
  • May not provide as much structural support as Restylane® in some areas.

Deeper-Dive on Key Restylane® Benefits

  • Wrinkle Smoothing: Restylane® excels in smoothing out wrinkles by filling in the creases and lines, giving your skin a more youthful and rejuvenated appearance. It's like a little boost of confidence every time you catch a glimpse of yourself in the mirror.
  • Volume Restoration: Restylane® is also a fantastic option for adding volume to sunken areas. As we age, our skin can lose its plumpness, resulting in hollowed-out areas that can make us look tired and worn out. With Restylane®, you can say goodbye to those sunken cheeks and hello to a more vibrant and youthful complexion.
  • Lip Enhancement: Let's not forget about enhancing your lips. Whether you're looking for a subtle enhancement or a more dramatic pout, Restylane® can help you achieve the perfect balance. Say goodbye to thin and lackluster lips and hello to a luscious and kissable smile.

Additionally, Restylane® treatments are suitable for individuals of various skin types and tones, making it an inclusive option for those looking to enhance their features. So, whether you have fair skin, dark skin, or anything in between, Restylane® can work its magic and help you achieve the look you desire.

Deeper-Dive on Key Juvéderm® Benefits

Juvéderm® is an excellent choice for individuals seeking facial rejuvenation. Its smooth formulation makes it ideal for addressing fine lines, wrinkles, and nasolabial folds, providing a refreshed and revitalized appearance.

  • Fine Line Smoothing: When it comes to fine lines and wrinkles, Juvéderm® is like a magic eraser, smoothing away those pesky signs of aging and leaving you with a more youthful and radiant complexion. It's like turning back the hands of time, one injection at a time.
  • Facial Contouring: But that's not all Juvéderm® can do. It's also a fantastic option for enhancing facial contours. Whether you want to define your cheekbones, sculpt your jawline, or restore volume to your temples, Juvéderm® can help you achieve the facial symmetry and balance you desire.
  • Lip Plumping: And let's not forget about plumping up those lips. Juvéderm® can give you the perfect pout, whether you're looking for a subtle enhancement or a more dramatic change. Say goodbye to thin and lifeless lips and hello to a plump and irresistible smile.
  • Cheek Volume Restoration: Furthermore, Juvéderm® can be used to restore volume loss in the cheeks. As we age, our cheeks can lose their youthful fullness, resulting in a hollowed-out appearance. With Juvéderm®, you can bring back that youthful plumpness and regain your confidence.

So, whether you're looking to smooth out fine lines, enhance your facial contours, plump up your lips, or restore volume to your cheeks, Juvéderm® has got you covered. It's like having a personal fountain of youth at your fingertips.

Choosing the Right Dermal Filler: Restylane® vs. Juvéderm®

Ultimately, the choice between Restylane® and Juvéderm® depends on your unique goals and the recommendations of a qualified healthcare professional. As an aesthetic nurse, you play a crucial role in guiding patients towards the most suitable dermal filler for their specific needs. Here are some key factors to consider when helping your patients make this decision:

  • Skin Concerns: Start by understanding your patient's primary skin concerns. Are they looking to address deep-set wrinkles, fine lines, or volume loss? Identifying their specific issues will guide you towards the most appropriate dermal filler.
  • Desired Outcomes: Discuss with your patients their desired outcomes. Do they want subtle enhancements or more dramatic results? Understanding their goals will help you recommend the right product and treatment plan.
  • Personal Preferences: Take into account your patient's personal preferences. Some individuals may prefer a particular product based on its reputation, manufacturer, or previous experiences.
  • Budget Considerations: While cost should not be the sole determining factor, it's essential to align the patient's budget with their expectations. Provide options and discuss financing if needed. Looking for help properly pricing your dermal fillers and other aesthetic treatments? Read more! Or read about how and when to raise your medspa cosmetic service pricing.
  • Product Expertise: As an aesthetic nurse, stay up-to-date with the latest advancements and research regarding Restylane® and Juvéderm®. Your expertise will inspire confidence in your patients.

Remember, both Restylane® and Juvéderm® are FDA-approved and have a long-standing reputation in the field of cosmetic dermatology. Whichever option you choose, you can feel confident knowing that both dermal products and tried and true for delivering great client results. 

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